Running XAMPP
When Running XAMPP, you will be greeted with this UI
You will then want to start MySQL and Apache (You can start FileZilla too if that's something you want although we will not cover that setup here).
Once you enable those, make sure their ports are open and available, if not, it should give you an error. (You will most likely want to remove whatever other program that is using their ports as they are default for the application usage).
Next up, you are going to want to make sure they start up with your system, click the Config button at the top right of the main UI.
(This is what should appear).
Make sure that both Apache and MySQL are check marked otherwise you will not be able to use them correctly together. Then press save.
Now Lastly, go back to the Main UI and press admin for the MySQL section. This will open your PhpMyAdmin which is your browser access to your local database information.